Since our March 2021 article, "Testing Shows High Levels of Benzene Found In Hand Sanitizers", more research has shown the carcinogen benzene contaminated 78 different sunscreens and sun care products. Benzene is a chemical that has been used in many different industries, but prolonged exposure to the chemical is known to cause acute myelogenous … [Read more...]
Tasigna Lawsuits Update: New Jersey MCL and Federal Court MDL Consolidations
We are currently investigating Tasigna side effects cases as possible Tasigna drug injury lawsuits against Novartis for patients who have developed some serious medical conditions during their use of Tasigna. In early June 2021, the New Jersey Supreme Court consolidated Tasigna drug injury lawsuits filed against Novartis Pharmaceuticals Corp. … [Read more...]
Vinorelbine extends PFS in relapsed malignant pleural mesothelioma
Vinorelbine combined with active supportive care conferred superior [ progression-free survival (PFS) ] compared with active supportive care alone among patients with relapsed malignant pleural mesothelioma, according to phase 2 study results. “All patients with malignant pleural mesothelioma eventually relapse following standard … [Read more...]
Environmental exposure to asbestos and the risk of lung cancer: a systematic review and meta-analysis
Asbestos is a carcinogen associated with lung cancer, but few studies have examined the increased risk of lung cancer due to environmental asbestos exposure. We performed a systematic review and meta-analysis to evaluate the association between environmental asbestos exposure and lung cancer. We searched for articles on non-occupational or … [Read more...]
Novartis Stops 3 Beovu Clinical Trials in May 2021, Wants a Beovu Label Change
In late May 2021, the latest study data concerning Beovu safety issues resulted in Novartis stopping three key clinical trials — MERLIN, RAPTOR, and RAVEN — as well as Novartis indicating there will be another Beovu label change. To see how Novartis is seeking to present the current status of its lingering Beovu safety issues as well as the next … [Read more...]
Ocaliva-related Liver Injury Warnings Will be Added to Ocaliva Drug Label
We now know more about the Ocaliva-related liver injury “safety signal” that the FDA has been investigating over the past year, and as a result of that Ocaliva FDA safety evaluation there will be an Ocaliva label change with new warnings. On May 26, 2021, this FDA Drug Safety Communication about Ocaliva, “Due to risk of serious liver injury, FDA … [Read more...]
Health groups sue to make EPA evaluate ‘legacy’ asbestos risk
Health and environmental groups have sued the Environmental Protection Agency [(EPA)], seeking a court order compelling it to evaluate the risks posed by so-called “legacy” asbestos used in old products and buildings. In a complaint filed Tuesday in federal court in San Francisco, groups including the nonprofit Asbestos Disease Awareness … [Read more...]
A 2021 Look at the Increased Risk of Elmiron-associated Pigmentary Maculopathy
We have reported previously on Elmiron-related eye damage, particularly that long-term use of the interstitial cystitis treatment drug Elmiron has been linked to maculopathy eye damage. In this post, we present a 2021 Elmiron medical journal article wherein it is estimated that around 20% of interstitial cystitis patients with long-term Elmiron use … [Read more...]
Why Asbestos Still Threatens Construction Workers’ Health
Asbestos continues to represent a considerable threat to the health of construction workers and the population at large. Though some applications for asbestos have been banned in the United States, the naturally occurring silicate mineral itself is not. The first use of asbestos is believed to date back to the Stone Age, approximately 750,000 … [Read more...]
Malignant pleural mesothelioma: Comparison of surgery-based trimodality therapy to medical therapy at two tertiary academic institutions
Objectives: Medical management based on palliative chemotherapy is currently the standard of care in malignant pleural mesothelioma (MPM). Median survival of 12–16 months has been reported with modern chemotherapy regimens with or without anti-angiogenic agents. Multimodality therapy incorporating cytoreductive surgery, systemic chemotherapy … [Read more...]
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