The [ combination immunotherapy consisting ] of nivolumab (Opdivo) and ipilimumab (Yervoy) offers a durable, long-term survival benefit over chemotherapy for patients with unresectable malignant pleural mesothelioma (MPM), confirms a 3-year updated analysis of the CheckMate 743 trial. After 3 years, 23% of patients who received combination … [Read more...]
Imbruvica Heart-Related Side Effects and Cardiotoxicity Safety Issues
In this article, we point out a few of the medical news reports about heart-related Imbruvica side effects that have been published in the past 12 months. First, there is this November 2020 Healio article, “Link between ibrutinib-related hypertension, heart problems necessitates close monitoring”, which provides some key findings from several … [Read more...]
Access to care varies greatly among patients with malignant pleural mesothelioma
Access to care varied significantly among patients with stage I to stage III malignant pleural mesothelioma, according to study results. The findings — presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer — showed variations in access based on factors such as distance to treatment facility, as well … [Read more...]
Possible New Xeljanz Side Effect: Peripheral Neuropathy
As reported in this Letters to the Editor item, “Tofacitinib and Risk of Peripheral Neuropathy? Experience of 2 Cases in Patients With Rheumatoid Arthritis”, patients treated with Xeljanz (tofacitinib) for their rheumatoid arthritis (RA) may be at risk of neurological adverse events, such as Xeljanz-related peripheral neuropathy. That item about … [Read more...]
More Data in Support of Surgery for Malignant Pleural Mesothelioma
Patients with malignant pleural mesothelioma (MPM) lived 6 months longer, on average, when they had surgery in addition to chemotherapy, a large retrospective analysis showed. The addition of surgery to combination chemotherapy resulted in a median overall survival (OS) of 22 months as compared with 16 months with chemotherapy alone. Twice as … [Read more...]
Appeals court reinstates suit by Solano County woman against Johnson & Johnson over baby powder
A state appeals court reinstated a lawsuit Tuesday by the widow of a Solano County man who died of cancer after using [ Johnson & Johnson Baby Powder ] for most of his life. A judge had dismissed the suit by Douglas Strobel and his wife, Jo Ann Strobel, saying their medical witnesses had no firsthand evidence that the talcum in [ Johnson … [Read more...]
Padcev Linked to SJS and TEN: From No Warning to “Black Box” in Less Than 2 Years
We are going to look at how the Padcev drug label went from having no warning about Padcev skin side effects Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) when approved by the FDA in December 2019 to the Padcev drug label having a “Black-Box” warning about the SJS and TEN skin side effects in July 2021, less than 2 years after … [Read more...]
Understanding the new therapeutic options for mesothelioma
Since the US Food and Drug Administration (FDA) approved pemetrexed plus cisplatin for first-line treatment of mesothelioma in 2004, there has been a dearth of additional treatment options for this disease. Despite substantial effort, no other phase 3 study achieved a positive outcome for another 12 years, until the MAPS trial showed that the … [Read more...]
Benzene Linked to Non-Hodgkin Lymphoma According to New Review of Past Studies
Exposure to benzene has been known to cause acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS). Now, as a result of new medical research has found a statistically significant association between exposure to benzene and non-Hodgkin lymphoma. Medical researchers recently examined the potential link between benzene exposure and … [Read more...]
Elmiron and Maculopathy: Two Recent Medical Articles About an Elmiron Vision Side Effect
In this post, we look at some relatively recent research regarding the still-emerging drug safety issue of Elmiron and maculopathy, i.e., maculopathy is an Elmiron vision side effect. According to “Screening needed for pentosan polysulfate sodium-associated maculopathy”, published on September 2, 2021, by Ocular Surgery News: In most cases, … [Read more...]
- « Previous Page
- 1
- 2
- 3
- 4
- …
- 58
- Next Page »