Given the serious nature and number of Beovu side effects reported to date, together with the Beovu lawsuits filed against Novartis for patients with severe vision loss, it seems fair to say that things look a bit grim for Beovu and Novartis at the start of 2021. So what does the path forward look like for Beovu? Let’s start with where things … [Read more...]
Notice Violation Issued to Chemours After Failure to Properly Remove PFAS Contamination
According to a January 2021 article "N.C. regulators issue notice of violation to Chemours", the company received a violation notice regarding a newly-installed treatment system that failed to remove PFAS contamination at the Fayetteville Works site. As mentioned in previous articles, the main offender for per- and polyfluoroalkyl substances (PFAS) … [Read more...]
Cell and extracellular matrix interaction models in benign mesothelial and malignant pleural mesothelioma cells in 2D and 3D in‐vitro
Malignant pleural mesothelioma (MPM) is an aggressive tumour that grows in the pleural cavity. [ Malignant pleural mesothelioma (MPM) ] spheroids released in the pleural fluid can form new tumour foci. Cell–cell, cell–extracellular matrix (ECM) interactions in 2D and 3D impact malignant cell behaviour during cell adhesion, migration, proliferation … [Read more...]
Maculopathy Patients Should be Asked About Any Elmiron Use in Past
A new Elmiron medical study about cases of macular toxicity related pentosan polysulfate (PPS) exposure suggests that established maculopathy patients should be questioned regarding any Elmiron use in the past. This will help eye doctors determine whether this person may have Elmiron maculopathy secondary to PPS toxicity. The findings of this … [Read more...]
Gilenya Label Change with New Liver Injury Risk Warnings in Canada
In the final two months of 2020, we saw a Gilenya label change adding new liver risk warnings announced by drug regulators in Europe, first, and the United Kingdom (UK), later. Next, in January 2021, Health Canada posted a Gilenya drug safety alert about patients developing Gilenya-associated liver injury, including acute liver failure … [Read more...]
Surgery for malignant pleural mesothelioma after radiotherapy (SMART): final results from a single-centre, phase 2 trial
Background: A novel approach for managing malignant pleural mesothelioma, surgery for mesothelioma after radiotherapy (SMART), consisting of a short accelerated course of high-dose, hemithoracic, intensity modulated radiotherapy (IMRT) followed by extrapleural pneumonectomy was developed. The aim of this study was to evaluate the clinical … [Read more...]
Talc-Based Beauty Products Found to be Contaminated With Asbestos
Talc-based beauty products have been found to be contaminated with asbestos according to some recent news headlines. How can this be? For years, cosmetics and personal care products have included a mineral ingredient called talc in their manufacturing process. Talc’s original intention was to improve the texture and feel of products, … [Read more...]
Elmiron Legal Cases for Eye Damage and Retinal Injury Are Consolidated in Elmiron MDL
In December 2020, all Elmiron legal cases alleging eye damage and retinal injury filed in the federal courts were consolidated by means of an Elmiron MDL Order. These Elmiron legal cases are noteworthy as regards the monetary damages aspect of a lawsuit because these Elmiron-related eye problems can lead to vision loss or blindness. From the … [Read more...]
Additional PFAS Testing Petition Denied by the EPA
Since our last article, “PFAS Levels in Cape Fear Remain Largely the Same, Despite Emission Cuts“, the Cape Fear region continues to experience high levels of “forever chemicals” in their water supply. Despite requests for additional PFAS testing, no additional regulations have been put in place. As mentioned in previous articles, the main … [Read more...]
Beovu: What Comes Next for This Troubled Novartis AMD Eye Injection?
As we start 2021, let’s look at where things currently stand with the Beovu “safety issue” — Beovu adverse drug reactions and Beovu-related eye problems — and how we got here. In the 15 months since Beovu was approved by the FDA in October 2019, there have been numerous reports of Beovu causing occlusive retinal vasculitis, retinal artery … [Read more...]
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