On September 1, 2021, we saw new FDA Xeljanz warnings about the increased risks of heart attacks, strokes, cancer, blood clots, and deaths. These Xeljanz drug safety problems have been associated with all doses of Xeljanz (5 mg tablet and 10 mg tablet) and Xeljanz XR (11 mg tablet and 22 mg tablet). This September 2021 document, “FDA requires … [Read more...]
Surgery After Radiotherapy May Improve Outcomes in Patients with Malignant Pleural Mesothelioma
A particular surgery performed following the completion of radiotherapy treatment among a group of patients with malignant pleural mesothelioma was associated with improved outcomes including overall survival, according to study results recently published in Lancet Oncology. “Different treatment strategies have been tried (for malignant pleural … [Read more...]
Tongue: the unusual site in malignant pleural mesothelioma
Malignant mesotheliomas (MMs) are malignancies of the mesothelium, with primary deposits originating in the pleura, peritoneum, pericardium and the tunica vaginalis (ie, testicular). Metastatic spread is commonly reported to affect the liver, adrenal glands, kidney and contralateral lung (in cases of malignant pleural mesothelioma). Metastases to … [Read more...]
Tasigna Drug Injury Lawsuits Federal Court MDL Consolidation Order
There is a newly created Tasigna multi-district litigation (MDL) for those Tasigna drug injury lawsuits filed in the federal court system. We get some of the reasoning for this consolidation of Tasigna side effects cases from the August 10, 2021, JPML Transfer Order issued for IN RE: TASIGNA (NILOTINIB) PRODUCTS LIABILITY LITIGATION, MDL No. … [Read more...]
Court upholds award to family of worker who died of asbestos exposure
The South Carolina Supreme Court [in August 2021] upheld a $16 million jury award to the family of a maintenance worker at a polyester fiber plant who died following years of asbestos exposure. Hystron Fibers Inc., owned by defendant CNA Holdings, hired Daniel Construction Co. in 1965 to build a plant in Spartanburg, South Carolina. When the … [Read more...]
Some Research Resources for Drug Safety and Warnings Information
For various reasons, one may be interested in finding drug safety and side effects warnings information. Here are three reliable research resources from the FDA which will get you started: Drugs@FDA: FDA-Approved Drugs from the U.S. Food and Drug Administration For prescription brand-name drugs, Drugs@FDA typically includes the most recent … [Read more...]
Comparative effectiveness of second-line immune checkpoint inhibitor therapy versus chemotherapy for malignant pleural mesothelioma
Objectives: Second-line immune checkpoint inhibition (ICI) was recently shown to have a survival advantage over placebo in malignant pleural mesothelioma (MPM), but the survival comparison to chemotherapy in patients with MPM receiving routine clinical care is unknown. Our objective was to examine the effectiveness of second-line ICI versus … [Read more...]
Drug Injury Lawsuits: List of Some Cases Filed in First Half of 2021
A drug injury lawsuit is a personal injury case or a wrongful death case involving a serious drug side effect or a severe adverse drug reaction. Here are some of the prescription medications for which drug injury lawsuits were filed against the responsible pharmaceutical company in the first half of 2021: Xeljanz Beovu Elmiron … [Read more...]
Neoadjuvant pemetrexed plus cisplatin followed by pleurectomy for malignant pleural mesothelioma.
PURPOSE: Despite becoming the preferred surgical technique for malignant pleural mesothelioma, pleurectomy/decortication has received few prospective clinical trials. Therefore, the Japan Mesothelioma Interest Group conducted a prospective multi-institutional study to evaluate the feasibility of neoadjuvant chemotherapy followed by … [Read more...]
Johnson & Johnson Recalls Neutrogena and Aveeno Sunscreen Over Benzene Contamination Concerns
As previously mentioned in our June 2021 article, "Are Benzene Contaminated Sunscreens Safe to Use?", popular sunscreen manufacturer, Johnson & Johnson has issued a voluntary recall of five Neutrogena and Aveeno aerosol sunscreen products. According to the Food and Drug Administration (FDA)'s July 2021 Safety Notice, the company conducted … [Read more...]
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