Now that a new standard of care has been established in frontline mesothelioma, clinical trials are needed to evaluate optimal sequencing with checkpoint inhibitors in the salvage setting and determine whether biomarkers of response to immunotherapy could further tailor treatment to individual patients [ with unresectable pleural mesothelioma ], … [Read more...]
Asbestos inhalation poses cancer risks to workers and consumers
The processing and use of asbestos-containing diaphragms by the chlor-alkali industry poses an unreasonable risk to the health of workers, the US Environmental Protection Agency concludes in a draft risk evaluation. The assessment, released March 30, also finds unreasonable risks to workers and consumers who process or use asbestos-containing sheet … [Read more...]
EPA finds asbestos poses cancer risks for workers, reigniting calls for ban
The Environmental Protection Agency (EPA) has determined that [ asbestos dust ] poses an unreasonable risk of [ lung cancer and mesothelioma ] to both workers and consumers who inhale it, ramping up pressure on the agency to ban the substance. In a draft risk assessment published this week, the EPA said that workers who inhale [ asbestos dust ] … [Read more...]
Montana Supreme Court: BNSF Not Shielded from Liability in Libby Asbestos Cases
In a unanimous decision, the Montana Supreme Court on Wednesday determined that BNSF Railway Company is not shielded from liability for its role in spreading asbestos-laden dust in the Northwest Montana town of Libby, where hundreds of people [ who developed asbestos-related disease ] have died and thousands more are sick due to … [Read more...]
Asbestos Warnings Grow With Penn State Lawsuit, National Push
Peter Labosky Jr. had been retired for 12 years from his job as a professor of wood sciences at Penn State University when he was diagnosed in 2014 with mesothelioma. He died five months later. [This case is an example of a “new” or non-traditional asbestos litigation area.] Mr. Labosky’s family alleges in a lawsuit filed in 2016 that the … [Read more...]
Malignant Diffuse Mesothelioma in Women — A Study of 354 Cases
We reviewed 354 cases of malignant diffuse mesothelioma (MM) in women from a database of 2858 histologically confirmed MM cases. There was a pleural predominance with 78% [ pleural malignant mesothelioma ] and 22% [ peritoneal malignant mesothelioma ]. The pleural tumors consisted of 72% epithelioid, 19% biphasic, and 9% sarcomatoid variant. The … [Read more...]
State Proposes ‘Asbestos Watch Area’ Near Old Davidson Mill
State environmental officials want to designate part of the west side of Davidson as an “asbestos watch area.” But the renewed discussion about asbestos from an old factory nearby is reviving concerns among residents in the historically African American neighborhood. The neighborhood around the former Carolina Asbestos factory near downtown … [Read more...]
Powder Keg: FDA bowed to industry for decades as alarms were sounded over talc
At an invitation-only gathering late last year, U.S. regulators and their guests huddled at a hotel near Washington, D.C., to discuss the best way to detect cancer-causing asbestos in talc powders and cosmetics. The “Asbestos in Talc Symposium,” sponsored by the Food and Drug Administration [ and intended to investigate asbestos in talc powders … [Read more...]
Cancer in the classroom
[Lea DiRusso was exposed to asbestos while teaching at schools for nearly 30 years, then this teacher is diagnosed with mesothelioma.] Every week during the school year, teacher Lea DiRusso climbed on a chair and hung her students’ best work on a clothesline strung between two old heating pipes. As she tugged the line down to clip on artwork or … [Read more...]
Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant mesothelioma: therapeutic implications
Introduction: We compared the secretome of metastatic (non-small cell lung cancer (NSCLC)) and primary (mesothelioma) malignant pleural effusions, benign effusions and the published plasma profile of patients receiving chimeric antigen receptor T cells (CAR-T), to determine factors unique to neoplasia in pleural effusion (PE) and those accompanying … [Read more...]
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