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The presence of pleural effusion is an independent prognostic factor in patients with malignant pleural mesothelioma

January 7, 2025 By Law Offices of Thomas J. Lamb, P.A.

Abstract:  Malignant pleural mesothelioma (MPM) is a rare form of thoracic malignancy with a poor prognosis. Pleural effusion (PE) occurs in the majority of patients with MPM; however, its impact on MPM outcomes remains controversial. We searched for eligible patients from the Surveillance, Epidemiology, and End Results (SEER) database, and … [Read more...]

Filed Under: Mesothelioma Tagged With: malignant pleural mesothelioma (MPM), mesothelioma, mesothelioma diagnosis

Andexxa Drug Injury Lawsuits for Blood Clots, PE, DVT

January 7, 2025 By Law Offices of Thomas J. Lamb, P.A.

Andexxa (andexanet) is a treatment currently used when the reversal of anticoagulation is needed for life-threatening or uncontrolled bleeding in patients who are using Eliquis (apixaban) or Xarelto (rivaroxaban) at the time.  Andexxa drug injury lawsuits for patients who developed blood clots involving a pulmonary embolism (PE) or deep vein … [Read more...]

Filed Under: Unsafe Drugs Tagged With: andexxa, blood clots, Deep Vein Thrombosis (DVT), drug injury lawsuits, Pulmonary Embolism (PE)

Ozempic Vision Loss Due to Increased Risk of NAION

December 20, 2024 By Law Offices of Thomas J. Lamb, P.A.

Here is the most recent development concerning Ozempic vision loss and blindness: The European Union’s drug regulator said it would assess two new Danish studies that link Novo Nordisk’s popular diabetes drug Ozempic to a rare eye disease. The studies published earlier this week had found Ozempic significantly increases the risk of type 2 … [Read more...]

Filed Under: Unsafe Drugs Tagged With: blindness, Nonarteritic Anterior Ischemic Optic Neuropathy (NAION), Ozempic, Rybelsus, vision loss, Wegovy

Diffuse Pleural Mesothelioma: A Challenge in Early Diagnosis

December 17, 2024 By Law Offices of Thomas J. Lamb, P.A.

Abstract:  We present the clinical case of a 58-year-old female patient, a smoker with occupational exposure to respiratory toxins, who was admitted to our clinic following evaluation in an emergency department, where she was diagnosed with a moderate right pleural effusion. Upon admission, the patient exhibited respiratory symptoms, including … [Read more...]

Filed Under: Asbestos, Mesothelioma Tagged With: dyspnea, malignant pleural mesothelioma (MPM), mesothelioma, mesothelioma diagnosis, pleural mesothelioma

Ocaliva Label Change Possible After December 2024 FDA Alert

December 16, 2024 By Law Offices of Thomas J. Lamb, P.A.

The FDA issued an Ocaliva FDA drug safety alert in December 2024 that may result in another Ocaliva label change.  This alert was for cases of liver transplants and liver-related deaths among patients without pre-existing cirrhosis who used Ocaliva as a treatment for primary biliary cholangitis (PBC). To provide context for this most recent … [Read more...]

Filed Under: Unsafe Drugs Tagged With: liver injury, liver transplants, Ocaliva

Andexxa Clotting-Related Deaths and Andexxa Blood Clots

November 25, 2024 By Law Offices of Thomas J. Lamb, P.A.

The FDA’s Cellular, Tissue, and Gene Therapies Advisory Committee recently discussed the increased risk of  Andexxa clotting-related deaths and Andexxa blood clots seen in the ANNEXA-I trial done for Andexxa, compared with a standard of care reversal agent. This Andexxa Advisory Committee considered the current drug safety profile of Andexxa in … [Read more...]

Filed Under: Unsafe Drugs Tagged With: andexxa, blood clots

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline

November 21, 2024 By Law Offices of Thomas J. Lamb, P.A.

Introduction The purpose of this guideline is to provide recommendations for the management of patients with malignant pleural mesothelioma (MPM), an aggressive tumor with a poor prognosis. In the United States, about 3,000 new cases are diagnosed each year. The median overall survival of patients with advanced surgically unresectable disease is … [Read more...]

Filed Under: Mesothelioma Tagged With: mesothelioma, mesothelioma diagnosis, mesothelioma treatments

Depo-Provera Meningioma Brain Tumors Drug Injury Lawsuits

October 18, 2024 By Law Offices of Thomas J. Lamb, P.A.

Because the current drug label for Depo-Provera Contraceptive Injection (version “Revised: 7/2024”, accessed 10/16/24) does not include any warning about an increased risk of intracranial meningioma, we are investigating possible Depo-Provera meningioma brain tumors drug injury lawsuits seeking legal compensation for women who have been diagnosed … [Read more...]

Filed Under: Unsafe Drugs Tagged With: brain tumors, Depo-Provera, drug injury lawsuits, intracranial meningioma

Immunotherapy for Treatment of Pleural Mesothelioma: Current and Emerging Therapeutic Strategies

October 11, 2024 By Law Offices of Thomas J. Lamb, P.A.

Pleural mesothelioma is a rare malignancy associated with asbestos exposure and very poor prognosis, with a 5-year overall survival of 12%. Outcomes may vary according to stage at time of diagnosis and histologic subtype. Most recently, clinical trials utilizing dual checkpoint inhibitor regimens and chemotherapy in combination with immune … [Read more...]

Filed Under: Mesothelioma Tagged With: immunotherapy, mesothelioma treatments, pleural mesothelioma

No Federal Preemption for Fosamax MDL Femur Fracture Lawsuits: September 2024 Update

October 3, 2024 By Law Offices of Thomas J. Lamb, P.A.

The United States Court of Appeals for the Third Circuit recently issued this opinion, In re: Fosamax (alendronate sodium) Products Liability Litigation, No. 22-3412, (3d Cir. Sept. 20, 2024), ruling that there is no federal preemption for more than 500 Fosamax MDL femur fracture lawsuits that had been dismissed previously and therefore, should now … [Read more...]

Filed Under: Unsafe Drugs Tagged With: federal preemption, Femur Fractures, Fosamax

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1908 Eastwood Road, Suite 225
Wilmington, North Carolina 28403
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