In this Drug Safety Update document, “Tofacitinib (Xeljanz▼): new measures to minimise risk of major adverse cardiovascular events and malignancies”, the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) took new regulatory action regarding the Xeljanz risk of cardiovascular events as well as the Xeljanz risk of cancers, or … [Read more...]
Xeljanz: Heart Attacks, Strokes, Cancers, Blood Clots, and Deaths – Updated FDA Warnings 2021
On September 1, 2021, we saw new FDA Xeljanz warnings about the increased risks of heart attacks, strokes, cancer, blood clots, and deaths. These Xeljanz drug safety problems have been associated with all doses of Xeljanz (5 mg tablet and 10 mg tablet) and Xeljanz XR (11 mg tablet and 22 mg tablet). This September 2021 document, “FDA requires … [Read more...]
Johnson & Johnson Recalls Neutrogena and Aveeno Sunscreen Over Benzene Contamination Concerns
As previously mentioned in our June 2021 article, "Are Benzene Contaminated Sunscreens Safe to Use?", popular sunscreen manufacturer, Johnson & Johnson has issued a voluntary recall of five Neutrogena and Aveeno aerosol sunscreen products. According to the Food and Drug Administration (FDA)'s July 2021 Safety Notice, the company conducted … [Read more...]
FDA Advisory Committee Meeting Could Review Risk/Benefit Profiles for All JAK Inhibitors
The FDA has delayed its decision for Abbvie’s applications to have Rinvoq approved for the additional indications of psoriatic arthritis and ankylosing spondylitis, apparently due to possible new JAK inhibitors heart side effects and cancer risks issues identified in connection with a Xeljanz safety signal. From this June 25, … [Read more...]
Are Benzene Contaminated Sunscreens Safe to Use?
Since our March 2021 article, "Testing Shows High Levels of Benzene Found In Hand Sanitizers", more research has shown the carcinogen benzene contaminated 78 different sunscreens and sun care products. Benzene is a chemical that has been used in many different industries, but prolonged exposure to the chemical is known to cause acute myelogenous … [Read more...]
Possible FDA Advisory Committee Meeting for Xeljanz, Olumiant, and Rinvoq in Future
Based on these several recent developments, we expect that there will be an FDA Advisory Committee Meeting for Xeljanz, Olumiant, and Rinvoq in the months to come. The focus of such will likely be these adverse drug events and side effects related to the JAK inhibitors class of drugs: Heart AttacksMyocardial Infarction (MI)Strokes — Ischemic / … [Read more...]
Are Heart Problems and Cancers JAK Inhibitors Drug Class Safety Issues?
Since the February 2021 FDA alert about Xeljanz-associated heart problems and possible Xeljanz-related cancers was issued, we have been watching for any related drug safety developments concerning Olumiant and Rinvoq. The reason being there has been some concern that those adverse drug events and side effects risks may apply to those other two … [Read more...]
New Data Released on Risk of Lymphoma Due to Breast Implants
Recent Study on BIA-ALCL RisksSince my last article on this topic, "What is the Risk of Death Due to Breast Implant-Associated Lymphoma?," additional information on the risk of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) has been released. The most recent study, titled "Breast Implants and the Risk of Anaplastic Large-Cell … [Read more...]
Breast Implant-Associated Lymphoma Diagnoses on the Rise
On October 18, 2017, the JAMA Surgery journal published an article titled "Breast Implant–Associated Anaplastic Large Cell Lymphoma A Systematic Review," in which they discuss the rate of occurrence of the condition. The article served as a review of 115 articles on the topic of breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) … [Read more...]
Breast Implants and Lymphoma: Who’s to Blame?
As previously discussed in my articles, "Breast Implants Linked to Rare Lymphoma Blood Cancer" and "Breast Implant Lymphoma: Causes Uncertain, but Costs Undeniable, the FDA recently updated their 2011 report of the association between breast implants and anaplastic large-cell lymphoma (ALCL), providing additional information on this rare form of … [Read more...]