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Can SGLT-2 Inhibitor Diabetes Drugs Increase Your Risk of Stroke?

June 21, 2017 By Law Offices of Thomas J. Lamb, P.A.

While we have frequently discussed DKA, kidney damage, and amputations as possible side effects of diabetes drugs in the SGLT-2 inhibitors class -- such as Farxiga, Invokana, Jardiance -- strokes and thromboembolic events are also considered potential harmful effects of these drugs. Based on FAERS reports received during the second quarter of … [Read more...]

Filed Under: Unsafe Drugs Tagged With: Acute Kidney Injury, Amputations, antidiabetic drugs, canagliflozin, canagliflozin/metformin HCl, causes of stroke, dapagliflozin, dapagliflozin/metformin HCl, Deep Vein Thrombosis, diabetes drugs, diabetic ketoacidosis, DKA, drug injury lawsuits, drug side effects, DVT, empagliflozin, empagliflozin/linagliptin, empagliflozin/metformin HCl, Farxiga, FDA, FDA FAERS reports, Glyxambi, Invokamet, Invokana, Jardiance, Kidney Damage, Kidney Failure, lower limb amputations, PE, Pulmonary Embolism, SGLT-2 inhibitors, Stroke, Synjardy, thromboembolic events, Xigduo, xigduo xr

Invokana Shown to Have Heart Benefits, but Elevated Amputation Risks

June 13, 2017 By Law Offices of Thomas J. Lamb, P.A.

Type 2 diabetes drug Invokana (canagliflozin) was the subject of the Canagliflozin Cardiovascular Assessment Study (CANVAS) and the CANVAS renal-end-points trial (CANVAS-R).  While it was recently shown to have significant cardiovascular benefits, it also carries double the risk of lower-limb amputations. In terms of cardiovascular event … [Read more...]

Filed Under: Unsafe Drugs Tagged With: amputation risks, canagliflozin, Canagliflozin Cardiovascular Assessment Study, CANVAS, CANVAS renal-end-points trial, CANVAS-R trial, dapagliflozin, diabetes drugs, empagliflozin, Farxiga, Invokana, Jardiance, sglt2 inhibitors

Risk of Lower Limb Amputations Doubled with Invokana and Invokamet Use

May 17, 2017 By Law Offices of Thomas J. Lamb, P.A.

As of yesterday, May 16, 2017, the FDA issued a Drug Safety Communication regarding an increased risk of leg and foot amputations due to use of popular diabetes drugs Invokana, Invokamet, and Invokamet XR, which contain canagliflozin. These drugs belong to the sodium glucose cotransporter 2 (SGLT2) inhibitor class, and are the subjects of … [Read more...]

Filed Under: Unsafe Drugs Tagged With: Amputations, canagliflozin, dapagliflozin, drug injury, EMA, empagliflozin, Farxiga, FDA, foot amputations, Invokamet, Invokana, Jardiance, leg amputations, sglt2 inhibitors, side effects, toe amputations, Xigduo, xigduo xr

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