Question: Can Depo-Provera legal compensation cases still be filed after a meningioma warning was added in December 2025 to the Depo-Provera drug label?
Short Answer: Yes, new Depo-Provera lawsuits can be filed if you received a Depo-Provera injection before December 2025, and were diagnosed with meningioma any time after those injections.
Discussion and Explanation of
Depo-Provera Legal Compensation Cases
After 2025 Meningioma Warning
1) The Meningioma Warning Added to Depo-Provera Drug Label in December 2025
Here is the current FDA-approved Depo-Provera Prescribing Information “Revised 12/2025” version (PDF document), in its Warnings and Precautions section, showing what was added to the Depo-Provera drug label in December 2025:
5.4 Meningioma
Cases of meningiomas have been reported following repeated administration of medroxyprogesterone acetate, primarily with long term use. Monitor patients on Depo-Provera CI for signs and symptoms of meningioma. Discontinue Depo-Provera CI if a meningioma is diagnosed.
2) Reason For Adding This New Side Effect Warning About Meningioma
The reason for adding this new meningioma warning is that a woman should be informed of all serious side-effect risks associated with a Depo-Provera injection before the time it is given. Before the December 2025 Depo-Provera label change, there was no meningioma warning in any of the previous Depo-Provera drug labels, also known as the Prescribing Information documents.
3) The Effect of This New Meningioma Warning on Depo-Provera Lawsuits
Two important points about what this new Depo-Provera meningioma warning means for new Depo-Provera legal compensation cases after 2025:
- First, as stated above, before the December 2025 label change, there was no Depo-Provera meningioma warning in the (previous) Depo-Provera Prescribing Information documents.
- Second, there is a delay — medically referred to as a “latency period” — from the time when a woman has Depo-Provera injections until that woman develops meningioma symptoms and is later diagnosed with a type of meningioma by a medical doctor.
Accordingly, a woman who used Depo-Provera before December 2025 can file a new Depo-Provera lawsuit in 2026 alleging failure to warn about the meningioma side effect, regardless of whether their meningioma diagnosis was made before or after the December 2025 Depo-Provera “meningioma warning” label change.
4) Some Factors for New Depo-Provera Legal Compensation Cases
(A) The woman must have received at least 1 injection of any of the following:
-
- Brand name Depo‐Provera 150mg IM Injections (Upjohn, Pharmacia, Pfizer)
- Brand name Depo‐SubQ 104 Provera (Upjohn, Pharmacia, Pfizer)
- An “authorized generic” version of Depo‐Provera manufactured by Pharmacia & Upjohn Company LLC, Greenstone LLC, or Prasco Laboratories
(B) Some time thereafter, a medical doctor told this woman that she had developed one or more of these 23 “types” of meningioma (the specific label for the diagnosis made by that doctor):
-
- Meningioma
- Intracranial meningioma
- Intercranial meningioma
- Cranial meningioma
- Brain meningioma
- Meninges tumor
- Arachnoid tumor (but not arachnoid cyst)
- Convexity meningioma
- Falcine meningioma
- Parasagittal meningioma
- Intraventricular meningioma
- Skull base meningioma
- Sphenoid wing meningioma
- Olfactory groove meningioma
- Posterior fossa/petrous meningioma
- Suprasellar meningioma
- Recurrent meningioma
- Foramen magnum meningioma
- Meningothelial meningioma
- Fibrous meningioma
- Psammomatous meningioma
- Angiomatous meningioma
- Secretory meningioma
The Bottom Line for
Depo-Provera Legal Compensation Cases
After 2025 Meningioma Warning
You can file a new Depo-Provera legal compensation case after the 2025 meningioma warning under the following circumstances:
(a) If you used Depo-Provera before December 2025, and
(b) You received a meningioma diagnosis before or after the December 2025 Depo-Provera label change; then,
(c) You can file new Depo-Provera lawsuits in 2026 (or later) alleging failure to warn about the meningioma side effect.
Have a Possible Depo-Provera Legal Compensation Case?
Get a Drug Injury Lawyer Case Review Done For Free
To find out whether you might be able to file a Depo-Provera meningioma lawsuit, you can get a free case review done by drug injury lawyer Tom Lamb, who has represented patients in legal compensation cases filed against drug companies since 1999.
a) Online Case Evaluation Form Submission
— You can submit an Online Case Evaluation Form to get a legal review of your Depo-Provera use and meningioma diagnosis situation. This service is free, confidential, and there is no obligation. You will get a response from Tom Lamb no later than the next business day.
b) Phone Discussion About Possible Case
— You can call 910-256-2971 to speak with Tom Lamb about your Depo-Provera meningioma case. This phone consultation is also free, confidential, and there is no obligation.
Either way, you will get Tom Lamb’s impressions — not an intake person, a paralegal, or some other lawyer — about your possible new Depo-Provera lawsuit based on his many years of experience handling drug injury cases for patients who have developed serious side effects.
See some earlier articles about the legal and medical aspects of meningioma associated with Depo-Provera injections on our Drug Injury Law website:
- Meningioma With Depo-Provera Use Risk Factors Identified (November 2025)
- The Depo-Provera Warning About Meningioma in Europe (February 2025)
- Why Are There Depo-Provera Brain Tumor Warnings In Europe But Not US? (January 2025)
- Brain Tumors From Birth Control Depo-Provera Injections (October 2024)
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