In August 2016 the FDA sent letters to Janssen Pharmaceuticals and AstraZeneca Pharmaceuticals for label changes about fatal cases of ketoacidosis cases involving Invokana (canagliflozin), Invokamet (canagliflozin and metformin), Farxiga (dapagliflozin), and Xigduo XR (dapagliflozin and metformin extended-release). As for the other diabetes … [Read more...]
Viagra, Nexium, And Invokana: Drug Injury Lawsuits Report: Summer 2016
We are currently investigating possible drug injury lawsuits against the responsible pharmaceutical companies for patients who used the drugs listed below and developed certain side effects. (1) Erectile Dysfunction (ED) Pills, Benign Prostatic Hyperplasia (BPH) Medicines, and Pulmonary Arterial Hypertension (PAH) Medications in the … [Read more...]
Invokana / Farxiga / Jardiance: UTIs Then Urosepsis And Pyelonephritis
To date, most attention has been directed to the association between the sodium-glucose cotransporter-2 (SGLT2) inhibitors drugs and diabetic ketoacidosis (DKA). More recently, there was an FDA announcement concerning a label change about the acute kidney injury side effect. What has received less attention, it seems, is the fact that these … [Read more...]
Invokana / Farxiga / Jardiance: Amputations; Lactic Acidosis; Ketoacidosis
In July 2016 Boehringer Ingelheim Pharmaceuticals, Inc. received a Supplemental Approval letter from the FDA concerning a label change about fatal cases of ketoacidosis which have been reported concerning Jardiance, Synjardy, and Glyxambi. These relatively new diabetes medicines are part of the Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors … [Read more...]
All SGLT2 Inhibitors Now Investigated for Increased Risk of Amputation
As discussed in my post, Are Invokana & Invokamet Linked to Increased Risk of Toe Amputations?, the European Medicines Agency (EMA) warned in April of 2016 that the popular diabetes drugs, Invokana and Invokamet (canagliflozin), were linked to an increased risk of amputations, especially of the toes. These drugs belong to the sodium glucose … [Read more...]