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Prophylactic Radiotherapy for the Prevention of Procedure-Tract Metastases in Malignant Pleural Mesothelioma

August 17, 2016 By Law Offices of Thomas J. Lamb, P.A.

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This multicenter, open-label phase III study evaluated the utility of prophylactic radiation to prevent procedure-tract metastases in 203 patients with malignant pleural mesothelioma. No significant differences were observed in procedure-tract metastases incidence in those who received immediate radiotherapy vs those receiving deferred radiation therapy.

Routine universal prophylactic radiotherapy to prevent procedure-tract metastases in patients with malignant pleural mesothelioma offers no clear clinical benefit.

BACKGROUND

The use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed to compare prophylactic radiotherapy with deferred radiotherapy (given only when a PTM developed) in a suitably powered trial.

[Article continues at original source]

Source: Prophylactic Radiotherapy for the Prevention of Procedure-Tract Metastases in Malignant Pleural Mesothelioma

Filed Under: Asbestos, Mesothelioma Tagged With: asbestos cancer, asbestos-related disease, mesothelioma, mesothelioma treatments

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