There is new medical research concerning pancreatic cancer linked to diabetes medicines in the DPP-4 inhibitor drug class.
In more detail, the use of dipeptidyl peptidase-4 inhibitors (DPP-4i) diabetes medicines may be associated with an increased risk for pancreatic cancer in patients with newly diagnosed type 2 diabetes. This finding comes from an August 20, 2019 article published online by the Diabetes Care medical journal.
Some of the more popular diabetes medicines in the dipeptidyl peptidase-4 (DPP-4) inhibitor drug class are Onglyza (saxagliptin), Nesina (alogliptin), and Tradjenta (linagliptin).
From the Abstract for this Diabetes Care article, “Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase-4 Inhibitors”, we get the following information:
CONCLUSIONS: DPP-4i use is associated with increased risks of pancreatitis and pancreatic cancer in patients with newly diagnosed type 2 diabetes. However, the absence of increasing trend according to exposure duration suggests the chances of reverse causality, and long-term pancreatic safety of DPP-4i has to be further investigated.
We are watching for further developments about pancreatic cancer linked to diabetes medicines such as Onglyza, Nesina, and Tradjenta, as well as other dipeptidyl peptidase-4 (DPP-4) inhibitor diabetes drugs.
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