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Surgical Risk and Survival Associated With Less Invasive Surgery for Malignant Pleural Mesothelioma

March 19, 2019 By Law Offices of Thomas J. Lamb, P.A.

Objectives: We compared less invasive surgery with conventional surgery for malignant pleural mesothelioma (MPM).

Results: We included 152 patients (median age 64 [37–71] years; 131 men, 21 women), mostly with epithelioid subtypes (91.4%). Of them, 149 (98.0%) underwent neoadjuvant chemotherapy and 117 (77.0%) underwent surgery (60 had extrapleural pneumonectomy and 57 had pleurectomy/decortication). Macroscopic complete resection was achieved in 94.9% (111/117), and the mortality rates at 30 and 90 days were 1.7% (2/117) and 3.4% (4/117), respectively. The overall median survival time and progression-free survival for all 152 patients were 34.9 and 17.4 months. The overall median survival time for Groups 1, 2, and 3 were 18.5, 41.9, and 43.4 months, respectively. The progression-free survival for Groups 1, 2, and 3 were 12.0, 24.5, and 21.8 months, respectively.

Conclusions: Compared with conventional surgical techniques, less invasive surgery for MPM yielded lower surgical risks and comparable or improved survival.

[Read article in full at original source]

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